Early life and education
Guthrie was born in Roseburg, Oregon and grew up in Ashland, Oregon. As a youth, he attained the rank of Eagle Scout in the Boy Scouts of America. Guthrie attended Ashland High School, where he excelled in basketball, football, baseball, as well as the classroom, where he was class valedictorian. After high school, he attended Brigham Young University before transferring to Stanford University, where he was a starting pitcher on their baseball team.
Guthrie was the ace of the Stanford University staff and formed a battery with Ryan Garko. He pitched in the regionals that season against MAAC champion Marist College in the first game and won 5-3. His team made it all the way to the World Series final in Omaha, but lost 11-1 in the Championship to the Miami Hurricanes.
Guthrie was the first-round selection (22nd overall) of the Cleveland Indians in the 2002 Major League Baseball Draft. He signed with the Indians on October 3, 2002. His US $4 million contract for four years included a US $3 million signing bonus.
Guthrie spent most of 2006 season with the Triple-A Buffalo Bisons, but was twice called up to the majors to join the Cleveland Indians as a relief pitcher. He wore jersey number 57 for both the Bisons and the Indians. After being removed from the 40-man roster following the signing of Trot Nixon and with no remaining Minor League options, he was designated for assignment on January 19, 2007.
Guthrie was claimed off waivers by the Baltimore Orioles on January 29, 2007. Upon joining the team, he requested and was granted permission to wear uniform number 46 from then-executive vice president of baseball operations Mike Flanagan, who had worn it during his playing career with the ballclub..After starting the year in the Baltimore Orioles' bullpen and then moving into the starting rotation, Guthrie enjoyed a breakout year in 2007, becoming one of the best and most consistent pitchers in the American League. Through June 21 that year, he ranked 2nd in ERA and allowing more than two earned runs in just 1 out of 10 starts. He was also first in the AL in WHIP.
Through the end of July 2007, Guthrie had a 7-3 record in 17 starts to go with a sparkling 2.89 ERA and a 1.027 WHIP (second only to 2-time Cy Young award winner Johan Santana), albeit in only 124.7 innings of work. Guthrie's rise to unexpected success in the first half of the season led to consideration for the American League's Rookie of the Year Award.
In August of 2008, Guthrie recorded his first career complete game, defeating the Seattle Mariners 3-1. Throughout the 2008 season, Guthrie emerged as the staff ace of the Baltimore Orioles.
Guthrie pitched for Team USA in the 2009 World Baseball Classic. Guthrie pitched on Opening Day for the Orioles against the New York Yankees before a record Opening Day crowd at Camden Yards. Guthrie pitched six innings and gave up three runs. He was able to get a career high win total in 2010 with 11 although he lost 14.
Guthrie pitching for the Rockies
On February 6, 2012, Jeremy Guthrie was traded to the Rockies for pitchers Matt Lindstrom and Jason Hammel
Kansas City Royals
On July 20, 2012, Guthrie was traded to the Royals for left-handed starter Jonathan Sanchez.
At Stanford, he studied sociology; he continues to pursue his degree in the offseason. Guthrie is a member of The Church of Jesus Christ of Latter-day Saints, and he served a two-year mission for them in Spain. He lives in American Fork, Utah with his wife, Jenny and three children, including daughter, Avery, and older son, Hudson. The couple's second son was born on July 19, 2010. He also continues to be active in promoting the Scouting program among boys in the Baltimore Area Council.